Anti-cancer activity of novel dibenzo[b,f]azepine tethered isoxazoline derivatives

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Anti-cancer activity of novel dibenzo[b,f]azepine tethered isoxazoline derivatives

BACKGROUND Dibenzoazepine (DB) derivatives are important and valuable compounds in medicinal chemistry. The synthesis and chemotherapeutic properties of naturally occurring DBs and different heterocyclic moiety tethered DBs are reported. Herein, we report the DB-fused hybrid structure that containing isoxazolines (DBIs) and their anti-cancer activity, which could throw light on the structural a...

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ژورنال

عنوان ژورنال: BMC Chemical Biology

سال: 2012

ISSN: 1472-6769

DOI: 10.1186/1472-6769-12-5